Contributions of mutations in acrR and marR genes to organic solvent tolerance in Escherichia coli
نویسندگان
چکیده
منابع مشابه
Expression of acrA and acrB Genes in Esherichia coli Mutants with or without marR or acrR Mutations
Objective(s): The major antibiotic efflux pump of Esherichia coli is AcrAB-TolC. The first part of the pump, AcrAB, is encoded by acrAB operon. The expression of this operon can be kept elevated by overexpression of an activator, MarA following inactivation of MarR and AcrR repressors due to mutation in encoding genes, marR and acrR, respectively. The aims of this research were to us...
متن کاملExpression of tolC and organic solvent tolerance of Escherichia coli ciprofloxacin resistant mutants
AcrAB-TolC is a major efflux pump in Escherichia coli. It was reported that tolC is overexpressed and involves in improving the organic solvent tolerance level in Escherichia coli marR mutants that are resistant to several antibiotics, such as ciprofloxacin. Low and intermediate levels resistance did not improve organic solvent tolerance. Thus, in this descriptive-experimental study it was deci...
متن کاملExpression of tolC and organic solvent tolerance of Escherichia coli ciprofloxacin resistant mutants
AcrAB-TolC is a major efflux pump in Escherichia coli. It was reported that tolC is overexpressed and involves in improving the organic solvent tolerance level in Escherichia coli marR mutants that are resistant to several antibiotics, such as ciprofloxacin. Low and intermediate levels resistance did not improve organic solvent tolerance. Thus, in this descriptive-experimental study it was deci...
متن کاملexpression of acra and acrb genes in esherichia coli mutants with or without marr or acrr mutations
objective(s): the major antibiotic efflux pump of esherichia coli is acrab-tolc. the first part of the pump, acrab, is encoded by acrab operon. the expression of this operon can be kept elevated by overexpression of an activator, mara following inactivation of marr and acrr repressors due to mutation in encoding genes, marr and acrr, respectively. the aims of this research were to use e. coli m...
متن کاملExpression of acrA and acrB Genes in Esherichia coli Mutants with or without marR or acrR Mutations
OBJECTIVE(S) The major antibiotic efflux pump of Esherichia coli is AcrAB-TolC. The first part of the pump, AcrAB, is encoded by acrAB operon. The expression of this operon can be kept elevated by overexpression of an activator, MarA following inactivation of MarR and AcrR repressors due to mutation in encoding genes, marR and acrR, respectively. The aims of this research were to use E. coli mu...
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ژورنال
عنوان ژورنال: AMB Express
سال: 2012
ISSN: 2191-0855
DOI: 10.1186/2191-0855-2-58